Stirred, not shaken — Scientists uncover how transcription drives motion within the genome
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Apr-2025 05:08 ET (22-Apr-2025 09:08 GMT/UTC)
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome’s organization that directly affect gene regulation and expression. The findings bolster our understanding of the mechanics behind transcription-dependent motions of single genes—the dysfunction of which may lead to neurological and cardiovascular disorders as well as to cancer
Led by researchers at NYU Langone Health and its Perlmutter Cancer Center, a new study describes the development of a biologic, a drug derived from natural biological systems, that targets a mutant cancer protein called HER2 (human epidermal growth factor receptor 2) without attacking its nearly identical normal counterpart on healthy cells. Led by researchers at NYU Langone Health and its Perlmutter Cancer Center, a new study describes the development of a biologic, a drug derived from natural biological systems, that targets a mutant cancer protein called HER2 (human epidermal growth factor receptor 2) without attacking its nearly identical normal counterpart on healthy cells.