Engineers in the USC Alfred E. Mann Department of Biomedical Engineering have now developed an update to the tool that will allow CRISPR technology to be even more powerful with the help of focused ultrasound. The resulting toolkit will allow CRISPR gene editing to be precisely targeted to the specific areas requiring treatment. The research team is already applying this discovery to refine their work in cancer immunotherapy. The researchers are ".... are pushing it one step further to make it controllable. Instead of continuously editing the genome, we can now control it to be activated at a specific location and at a specific time using a non-invasive remote-controlled ultrasound wave. That’s the breakthrough.”

A study from the University of Michigan Health Rogel Cancer Center may have, at last, cracked the cold case of immunotherapy resistance.