Our congratulations to Ludwig Lausanne’s Johanna Joyce, who began her two-year term today as President of the European Association for Cancer Research (EACR), a global community of scientists and clinicians dedicated to advancing the scientific understanding of cancer and its application to improve patient care.

New research from Memorial Sloan Kettering Cancer Center (MSK) decodes how mesothelioma evades immunotherapy; shows why a common kidney cancer treatment combination falls short; and supports a free, open-source AI-driven drug discovery initiative.

Collagen, the protein that builds skin, bones, tendons and organs, exists inside cells as a liquid-like droplet rather than the long, rigid rod seen in textbooks over the last half century, according to a new study from the Centre for Genomic Regulation (CRG) in Barcelona.

Macrophages, immune cells often involved in inflammation, are regulated by the body clock (circadian clock). However, the underlying molecular mechanisms are not fully understood. Now, researchers from Kyushu University have discovered that the circadian clock protein BMAL1 transports the enzyme MFP2 into the cell nucleus, where MFP2 activates inflammatory genes and drives macrophages into a pro-inflammatory state. These findings open new possibilities for treating inflammatory diseases and cancer, potentially through timed drug therapies.