Maternal childhood trauma may lead to early metabolic changes in male children
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Apr-2025 04:08 ET (26-Apr-2025 08:08 GMT/UTC)
The antimalarial drug mefloquine could help treat genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy and some cancers.
Scientists at St. Jude Children’s Research Hospital and the Medical College of Wisconsin have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.
New multidisciplinary research led by Prof. Tomás Ryan from Trinity College Dublin shows that the brain forms memories of cold experiences and uses them to control our metabolism. This newly published study is the first to show that cold memories form in the brain – and map out how they subsequently drive thermoregulation.
The discovery may have important applications in therapies designed to treat a range of disorders – from obesity to cancer – in which thermoregulation and metabolism (or a lack of control in this area) plays a role, as well as opening the door to more fundamental research, which could help us better understand how memories impact our behaviour and emotions.
For many cancer patients, side effects from radiation can be debilitating. But a new way of delivering radiation treatment has proven effective at eliminating a hard-to-treat cancer with the only side effect being light skin discoloration, even nine months after treatment. This new treatment, step-and-shoot proton arc therapy, is the first to be used by physicians and scientists to treat a patient at Corewell Health William Beaumont University Hospital in Royal Oak, Michigan.