Immune cell research identifies potential new target for treating cancer and autoimmune disease
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Updates every hour. Last Updated: 28-Apr-2025 22:08 ET (29-Apr-2025 02:08 GMT/UTC)
The 2025 AACR-Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research will be presented to William N. Hait, MD, PhD, Fellow of the AACR Academy, during the AACR Annual Meeting 2025, to be held April 25-30 at the McCormick Place Convention Center in Chicago, Illinois.
Researchers at City of Hope have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterology study published today. Led by Mustafa Raoof, M.D., M.S., City of Hope assistant professor of surgery, cancer genetics and epigenetics, scientists focused on transcription-replication conflicts (TRCs), which occur when the mechanisms responsible for gene expression and genome duplication collide. The clash disrupts cells’ ability to read and copy genes, leading to replication stress, a frequent phenomenon in pancreatic cancer. The added stress causes cells to make errors copying their DNA, enabling cancer to gain a foothold and spread. Overall, the experimental approach was most effective at killing cancer cells with high replication stress, a common phenomenon that occurs when the KRAS gene goes awry.
A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable “cytokine factory” that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, pancreatic and colorectal tumors.
Researchers from the Agency for Science, Technology and Research (A*STAR) and the National Healthcare Group (NHG) have jointly pioneered an innovative imaging technique combining Multispectral Optoacoustic Tomography (MSOT) with artificial intelligence (AI) that could significantly improve the diagnosis and treatment of basal cell carcinoma (BCC), the most common form of skin cancer worldwide.
New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.