News Release

Endocrine disruptors and frog metabolic disorders

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

Adult <em>Xenopus tropicalis</em>

image: Adult Xenopus tropicalis. view more 

Credit: Image courtesy of Muriel Raveton.

Researchers report that tadpoles and mature adult female Xenopus tropicalis frogs exposed to two endocrine disruptors, benzo[a]pyrene and triclosan, at concentrations considered safe for human consumption developed metabolic disorders; frogs exposed to benzo[a]pyrene continued to exhibit symptoms after 1 year of cleansing in water; further, offspring of exposed frogs were smaller and lighter and experienced delayed metamorphosis and lower reproductive success, compared with controls, suggesting links between endocrine disruptors and amphibian population decline.

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Article #17-21267: "Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline," by Christophe Regnault et al.

MEDIA CONTACT: Stephane Reynaud, Université Grenoble Alpes, FRANCE; tel: +33683156129; e-mail: <stephane.reynaud@univ-grenoble-alpes.fr>


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