Study captures high-resolution reconstructions of ribosome dynamics in situ
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Apr-2025 18:08 ET (25-Apr-2025 22:08 GMT/UTC)
In a recent study published in Nature Structural & Molecular Biology, researchers led by Prof. ZHANG Xinzheng at the Institute of Biophysics, Chinese Academy of Sciences, utilized cryo-electron microscopy (cryo-EM) along with their self-developed algorithm, GisSPA, to capture dynamic, periodic changes in ribosomal translation within the cells of Saccharomyces cerevisiae—also known as Brewer’s yeast—at near-atomic resolution.
A research team led by Prof. HU Li at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode pain intensity and drive nociceptive-evoked gamma oscillations (GBOs).