News Release

Study shows that activity in the subthalamic nucleus reflects action outcomes and consequent adaptation in humans; this can be modified through bursts of electrical stimulation, with potential to restore healthy brain function in people with neurological

Peer-Reviewed Publication

PLOS

Study shows that activity in the subthalamic nucleus reflects action outcomes and consequent adaptation in humans; this can be modified through bursts of electrical stimulation, with potential to restore healthy brain function in people with neurological

image: In this study Herz et al. show that adaptive behaviour in humans can be facilitated by applying temporally patterned bursts of electrical stimulation to the subthalamic nucleus. view more 

Credit: Damian Herz (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)

Study shows that activity in the subthalamic nucleus reflects action outcomes and consequent adaptation in humans; this can be modified through bursts of electrical stimulation, with potential to restore healthy brain function in people with neurological disorders like Parkinson's disease.

#####

In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002140 

Article Title: Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior

Author Countries: United Kingdom, Germany

Funding: DMH is supported by a postdoctoral grant from the Independent Research Fund Denmark (0168-00014B). AP, HT and PB are supported by the Medical Research Council (MC_UU_00003/2). RB is supported by the Medical Research Council (MC_UU_00003/1). This research was funded by the UKRI [MC_UU_00003/2]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Journal

PLOS Biology

DOI

10.1371/journal.pbio.3002140

COI Statement

Competing interests: The authors have declared that no competing interests exist.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.