Genetic legacy of last glaciation influences reindeer’s seasonal migrations

Caribou (known as reindeer in Europe) make one of the longest seasonal migrations of land animals, but an individual’s propensity to migrate depends on its genetic ancestry, Maria Cavedon at the University of Calgary in Canada and colleagues report in a study publishing February 10^th in the open-access journal PLOS Genetics.

The researchers used GPS tracking and DNA sequencing to investigate the genetic factors influencing migratory behavior in 139 female reindeer (Rangifer tarandus) living in tundra or woodland habitats across western North America. They identified over 50 genetic mutations associated with migratory behavior, of which 27 were located in genes involved in brain activity, fat and energy metabolism, body development, or hormone production. The sequences clustered into northerly and southerly subpopulations, descended from ancestral caribou that were trapped either side of the Rocky Mountains during the last glaciation. Despite generations of hybridization since the glaciation ended around 11,000 years ago, the researchers found that caribou with a greater proportion of genes from northern ancestry were more likely to migrate longer distances. Migratory individuals travelled nearly 250 kilometers on average, ten times further than sedentary reindeer. These results indicate an evolutionary legacy from the last glaciation, when northerly caribou populations had to migrate to survive in harsh tundra environments, while southerly populations living in forests were more sedentary.

The study is the first to investigate the genes influencing migration in an endangered terrestrial mammal. Seasonal migrations allow animals to track moving resources or avoid harsh conditions, but they also make them particularly vulnerable to habitat fragmentation. Ancestral genes for migration could be lost forever if the descendants of northern lineages are driven extinct, but conserving key habitats in their seasonal migration routes could help to preserve the genes underpinning the world’s longest terrestrial migration, the authors say.

“Wide-ranging animals, including migratory species, are significantly threatened by the effects of habitat fragmentation and habitat loss,” Cavedon adds. “We examined migratory behavior of GPS-collared endangered caribou in western North America and carried out genomic scans for the same individuals. We detected genes associated with migratory behavior, and we determined that propensity to migrate depended upon the evolutionary history of caribou. If, as we report, migratory behavior is influenced by genes, caribou could be further impacted by the loss of the migratory trait in some isolated populations already at low numbers.”

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In your coverage, please use this URL to provide access to the freely available article in PLOS Genetics:

http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009974

Citation: Cavedon M, vonHoldt B, Hebblewhite M, Hegel T, Heppenheimer E, Hervieux D, et al. (2022) Genomic legacy of migration in endangered caribou. PLoS Genet 18(2): e1009974. https://doi.org/10.1371/journal.pgen.1009974

Author Countries: Canada, United States, United Kingdom

Funding: This work was supported by a student grant administered by Alberta Conservation Association (recipient MC, 2016 Award Recipient, http://www.acabiodiversity.ca/). The project (lead by MM) was funded by NSERC, www.nserc-crsng.gc.ca (recipient MM; RGPIN-2020-05286 and CRDPJ-538213-18-2019-2020) with matching by Alberta Innovates (recipient MM), Alberta Upstream Petroleum Research Fund (recipient MM), Canadian Association of Petroleum Producers (recipient MM), Canada's Oil Sands Innovation Alliance (recipient MM), Conoco-Phillips (recipient MM), Exxon (recipient MM), Teck Resources (recipient MM). In-kind contributions to the projects were made by the Governments of British Columbia, Alberta, Northwest Territories, and Yukon, and by Parks Canada. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.