Autism diagnosis by 2.5 years of age leads to dramatic improvements in social symptoms as compared to those diagnosed later in life, Ben-Gurion University researchers and colleagues find

BEER-SHEVA, Israel, November 17, 2021 – The potential benefits of early diagnosis and treatment of autism spectrum disorder (ASD) is at the heart of an ongoing debate about the necessity of universal screening for toddlers and the amount of funding that is allocated to facilitate early identification. Now, a new study by Ben-Gurion University of the Negev researchers and their colleagues clearly demonstrates that early diagnosis and treatment lead to considerable improvement in ASD social symptoms.

Their findings were published in the peer-reviewed journal Autism recently.

BGU's Prof. Ilan Dinstein, head of the Azrieli National Centre for Autism and Neurodevelopment Research, led a team who measured changes in core autism spectrum disorder symptoms over a 1–2-year period in 131 children diagnosed with autism spectrum disorder at 1.2– 5 years of age, and treated in the community. Community treatment is defined as regular treatment, in contrast to highly specialized intervention programs that are developed and studied in university settings. Previous studies had not examined whether children diagnosed before the age of 2.5 and treated in the community improve more than those diagnosed at later ages.

The results revealed that children who were diagnosed before 2.5 years of age were three times more likely to exhibit considerable improvements in the core social symptoms of autism in comparison to children diagnosed at later ages.

"We believe this larger improvement is due to the larger brain plasticity and behavioral flexibility that is a fundamental characteristic of early childhood," says Prof. Dinstein. "These results highlight the importance of early diagnosis and treatment of autism spectrum disorder even in community settings with heterogeneous services. In addition, these results motivate further prioritization of universal screening for autism spectrum disorder before 2.5 years of age."

"The study emphasizes how important it is that parents and professionals recognize the early signs of ASD," says Prof. Ditza Tzahor, director of ALUT's Autism Center at Shamir Medical Center, and Tel Aviv University, "Creating tools to assess ASD early is of great importance."

Prof. Ilan Dinstein is a member of the Departments of Psychology and Cognitive and Brain Sciences.

Additional researchers include Nitzan Gabbay Dizdar, Michal Ilan and Prof. Idan Menashe of Ben-Gurion University, Dr. Gal Meiri, Michal Faroy, Analya Michaelovski, Hagit Flusser of BGU and Soroka University Medical Center, Prof. Judah Koller of The Hebrew University of Jerusalem.

The study was supported by a National Autism Knowledge Center grant from the Israeli Ministry of Science and Technology.