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Mapping the Mutational Landscape of Tumors Using a New CRISPR Approach (1 of 2)

Reports and Proceedings

American Association for the Advancement of Science (AAAS)

Mapping the Mutational Landscape of Tumors Using a New CRISPR Approach (1 of 2)

image: Using viral vector based pooled genome editing, clinically relevant cancer mutations can be interrogated in a massive parallel manner directly in vivo. This material relates to a paper that appeared in the 28 February 2018, issue of Science Advances, published by AAAS. The paper, by G. Wang at Yale University School of Medicine in New Haven, CT, and colleagues was titled, "Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening." view more 

Credit: [Credit: Ryan D. Chow and Sidi Chen at Yale University]


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