News Release

Health care disparities seen in epilepsy patients with low socioeconomic status

More uncontrolled seizures and drug-related side effects found in this patient group

Peer-Reviewed Publication

Wiley

A newly published report reveals patients with epilepsy and low socioeconomic status (SES) are more likely to have uncontrolled seizures, drug-related side effects, and a lower overall quality of life. The study also indicates that low SES patients used the hospital emergency room more often and had more visits to a general practitioner than epileptic patients at higher socioeconomic levels. Full findings are now available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.

The Centers for Disease Control and Prevention (CDC) estimates that two million Americans have epilepsy and roughly 140,000 new cases are diagnosed each year. Prior studies in epilepsy literature provide evidence of disparities in healthcare use between individuals of different SES. One study found that epileptic patients with incomes below the poverty level in California were 50% less likely than those with higher income (not in poverty) to report taking epilepsy medication (Elliott et al., 2009).

"Current medical evidence is based on point-in-time comparisons across population and suggests that disparities in healthcare may be due to access difficulties," explains lead study author Dr. Charles E. Begley, Professor of Management & Health Sciences at the University of Texas Health Science Center in Houston. "Our study investigates disparities in healthcare over time, examining the impact of SES in patients with epilepsy who have access to regular care."

Researchers enrolled 566 adult patients with epilepsy from three clinics in Houston and New York City serving a low-SES population, and one in Houston serving high-SES patients. Participants were interviewed at baseline regarding healthcare use, seizure frequency and type, anti-epileptic drug (AED) side effects, and outcomes during the prior three-month and one-year periods. The survey was repeated several times during the year-long study period.

Indicators of SES—income, education, employment, and insurance coverage—were significantly lower for patients at low-SES sites compared to the higher-SES site. Patients at the low-SES sites had consistently higher emergency room use and visits to the general practitioner. Throughout the one-year study period low-SES patients had significantly higher likelihoods of poor outcomes—2.2 to 3.9 times more likely to have uncontrolled seizures and 4.9 to 16.3 times more likely to have AED side effects—compared with higher-SES patients.

The authors determined that significant disparities in patterns of care and outcomes of low and high-SES patients receiving regular care for epilepsy were persistent over the one-year study period. "Future research needs to examine specific site-related factors that may be associated with these disparities in care for individuals with epilepsy," concluded Dr. Begley.

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This study is published in Epilepsia. Media wishing to receive a PDF of this article may contact healthnews@wiley.com.

Full citation: "Socioeconomic status, healthcare use, and outcomes: Persistence of disparities over time." Charles Begley, Rituparna Basu, David Lairson, Thomas Reynolds, Stephanie Dubinsky, Michael Newmark, Forbes Barnwell, Allen Hauser and Dale Hesdorffer. Epilepsia; Published Online: February 14, 2010 (DOI: 10.1111/j.1528-1167.2010.02968.x). http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2010.02968.x/abstract.

Epilepsia is the leading, most authoritative source for current clinical and research results on all aspects of epilepsy. As the journal of the International League Against Epilepsy, subscribers every month will review scientific evidence and clinical methodology in: clinical neurology, neurophysiology, molecular biology, neuroimaging, neurochemistry, neurosurgery, pharmacology, neuroepidemiology, and therapeutic trials. For more information, please visit http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1528-1167.

Wiley-Blackwell is the international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons, with strengths in every major academic and professional field and partnerships with many of the world's leading societies. Wiley-Blackwell publishes nearly 1,500 peer-reviewed journals and 1,500+ new books annually in print and online, as well as databases, major reference works and laboratory protocols. For more information, please visit www.wileyblackwell.com or our new online platform, Wiley Online Library (wileyonlinelibrary.com), one of the world's most extensive multidisciplinary collections of online resources, covering life, health, social and physical sciences, and humanities.


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