video: This video shows migration of breast cancer cells in which β1 integrins were silenced. Cells migrate in collagen gel, starting at 48 hours post-injection for a duration of about three hours. This video relates to a paper that appeared in the Feb. 11, 2014, issue of Science Signaling, published by AAAS. The paper, by Hoa Truong at the Leiden Academic Center for Drug Research in Leiden, The Netherlands, and colleagues was titled, "β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer." view more
Credit: Video courtesy of <i>Science Signaling</i>/AAAS