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Correcting Cortical Defects and Seizures in Treatment-Resistant Epilepsy in Mice (2 of 2)

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American Association for the Advancement of Science (AAAS)

Correcting Cortical Defects and Seizures in Treatment-Resistant Epilepsy in Mice (2 of 2)

image: Co-immunostaining for filamin A (green) and a marker of diseased neurons, SMI-311 (red), and a nuclear stain DAPI (blue) counterstain in human FCDII tissue. This material relates to a paper that appeared in the Feb. 19, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by L. Zhang at Yale University School of Medicine in New Haven, CT; and colleagues was titled, "Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformations." view more 

Credit: [Credit: A. Bordey and L. Zhang]


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