Chemistry and biology of sulfur containing natural products from marine microorganisms

The intriguing chemistry and biology of sulfur?containing natural products from marine microorganisms (1987-2020) https://doi.org/10.1007/s42995-021-00101-2 Announcing a new publication for Marine Life Science & Technology journal. In this review article the authors Yang Hai, Mei?Yan Wei, Chang?Yun Wang, Yu?Cheng Gu and Chang?Lun Shao from Ocean University of China, Qingdao, China and Syngenta Jealott's Hill International Research Centre, Berkshire, UK consider the chemistry and biology of sulfur?containing natural products from marine microorganisms. Natural products derived from marine microorganisms are a potential source of new compounds for drug discovery. The marine environment hosts many sulfur-containing natural products with numerous biological functionalities, for example, antitumor, antibiotic, anti-inflammatory and antiviral properties. The authors of this article have provided a comprehensive overview of the sulfur-containing natural products that are non-sulfated and have been isolated from marine organisms. The overview covers the published literature from January 1987 to December 2020. A total of 484 compounds were recorded. Of these 59.9% were thioethers, 29.8% were thiazole/thiazoline-containing compounds and 10.3% were sulfoxides, sulfones, thioesters etc. A selection of 133 compounds were further discussed in relation to their structure-activity relationships, mechanisms of action, biosynthesis, and druggability.

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This article provides the most up to date review of sulfur-containing natural products from marine microorganisms from their first reporting in January 1987 to December 2020.

Article reference: Hai, Y., Wei, MY., Wang, CY. et al. The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987-2020). Mar Life Sci Technol (2021). https://doi.org/10.1007/s42995-021-00101-2

Keywords: Sulfur-containing natural products, marine microorganisms, molecular diversity, bioactivities, marine drugs

Marine Life Science & Technology (MLST) provides a platform that introduces new discoveries and theories associated with marine organisms, bioresources, and biotechnology. The journal is intended for marine scientists, biological oceanographers, conservation biologists, marine technologists, policy makers and legislators. Accordingly, we publish original research papers across a broad range of marine life sciences and technologies with an emphasis on synergistic interactions of multiple disciplines. Both theoretical and practical papers are welcome, including laboratory and field experimental studies relevant to marine life science and technology. Focused reviews, viewpoints, comments, and short communications are also accepted. As the journal's aim is to foster multidisciplinary approaches to marine sciences, authors are encouraged to emphasise the relevance of their work in relation across the journals key-disciplines.

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ISSN 2662-1746

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