video: MG53 can improve membrane repair in dystrophic muscle cells. This movie shows a similar dystrophic muscle fiber as in the previous movie (movie 2), however this fiber has been bathed in unlabeled MG53. When the cell is injured very little green dye can enter the cell, thus indicating that the presence of MG53 allows the cell membrane to repair more effectively. This video relates to a paper that appeared in the June 20, 2012 issue of Science Translational Medicine, published by AAAS. The paper, by Dr. N. Weisleder at Robert Wood Johnson Medical School in Piscataway, N.J., and colleagues, was titled, "Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy." view more
Credit: Video courtesy of UMDNJ-RWJMS