image: Poliovirus (left) and reovirus (right) virion images generated by cryo-electron microscopy and three-dimensional image reconstruction. Poliovirus is an enteric, neurotropic virus that occasionally causes paralysis in unvaccinated humans. Poliovirus image generated by Christopher M. Robinson, Ph.D. (University of Texas Southwestern Medical Center), based on structure coordinates from Miller et al., 2001, J Mol Biol 307: 499. Reovirus is an enteric, neurotropic virus that infects many mammalian species, including humans, but disease is restricted to the very young. This image relates to the paper by Dr. Kuss and colleagues. This image relates to a paper that appeared in the Oct. 14, 2011, issue of Science, published by AAAS. The paper, by Dr. Sharon Kuss of University of Texas Southwestern Medical Center in Dallas, Texas, and colleagues, was titled, "Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis." view more
Credit: Images courtesy of Christopher M. Robinson, Terence S. Dermody, and B. V. Prasad