image: Representative CT and PET/CT images of 3 patients with non-small cell lung cancers. (A) Patient with an EGFR exon 19 E746-A750 deletion who did not receive EGFR-TKI treatment, with a tumor in the right upper lobe of the lung (red arrow) (B) Patient with an EGFR exon 21 L858R point mutation, 15 days after gefitinib treatment. Tumor in the right upper lung lobe (red arrow) and spinal metastasis (yellow arrow) were observed both on 18F-MPG and 18F-FDG images. (C) Patient with wild-type EGFR who did not receive EGFR-TKI treatment. Tumor in the left hilum (red arrow) was prominently observed on the 18F-MPG image. view more
Credit: X. Sun <i>et al., Science Translational Medicine </i>(2018)