video: A proof-of-concept clinical trial shows that genetic engineering of the malaria parasite by the precise removal of three genes (called GAP3KO) creates a parasite strain that infects humans, but cannot cause malaria disease, and stimulates the immune system to mount protective responses. This video shows the procedure used to deliver the GAP3KO vaccine to human subjects through infected mosquito bites as well as a microscopic video of the motile parasite forms that constitute the vaccine. view more
Credit: Sebastian Mikolajczak, Center for Infectious Disease Research