image: In mice, activation of SIRT1 reduced lung inflammation during TB (right), compared to infected mice without SIRT1 (left). This material relates to a paper that appeared in the March 24, 2017, issue of Science Immunology, published by AAAS. The paper, by C.Y. Cheng at Agency for Science, Technology and Research (A*STAR) in Singapore, and colleagues was titled, "Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis." view more
Credit: Cheng <i>et al., Sci. Immunol.</i> 2, eaaj1789 (2017)