image: Heart muscle cells from the left ventricle of an aged, 2-year-old, female rat are shown. Vinculin (green) is located where muscle cells connect to each other and their microenvironment. Nuclei (blue) and actin (red) are also shown. This image relates to a paper that appeared in the June 17, 2015, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. Gaurav Kaushik at University of California, San Diego in La Jolla, Calif., and colleagues was titled, "Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart." view more
Credit: Gaurav Kaushik