37 percent of smokers fully switch to vaping blu after 90 days -- real-world study

Amsterdam, September 6th 2018 - A new peer-reviewed study funded by Fontem Ventures and published in the Journal of Environmental Research and Public Health of 72 adult smokers willing to try vaping as an alternative to smoking found that after 90 days, 37% of them had completely replaced their cigarettes and switched to the blu vaping products.

"Our data show that it is possible to facilitate significant behavioural change on the part of smokers as a result of providing them with access to high quality e-cigarette products, at least for a short period of time," said Professor Neil McKeganey, Director of Centre for Substance Use Research, who conducted the study.

The 72 adult smokers were given access to the blu PRO open system e-cigarette and a range of commercially available blu flavours and nicotine strengths through the duration of the study.

After 90 days the researchers found:

• 36.5% switched to vaping completely;
• Reduction in daily smoking from 88.7% of participants at baseline to 17.5%;
• Reduction in cigarettes per day from an average of 14.38 to an average of 3.19 per day;
• Decrease in the average number of days per month that participants smoked, from 27.87/30 at baseline to 9.22/30 days after 90-days.
• Non-tobacco flavour e-liquids were preferred by the majority of participants

The number of smokers who switched to vaping completely increased from baseline to day-30 and continued to rise throughout the study duration (90 days). The finding suggests that the use of vaping products may have additional benefits with longer use - i.e. a proportion of smokers completely switched within the first month of use, but a larger proportion needed more than 2 months to make the switch and gradually switch over a longer period.

"All participants found the flavours used were important in helping them to switch or cut down and 92.1% believed that the blu PRO had helped them to cut down or replace smoking completely at 90 days," said Professor McKeganey.

"In contrast to these impressive results, licensed nicotine replacement therapies have been shown to be substantially less satisfying to smokers as evidenced by their modest efficacy, in some cases less than 15% smoking abstinence after 3 months use*" said Dr Grant O'Connell, Corporate Affairs Manager, Fontem Ventures.

"The 40% of UK smokers who have not even tried an e-cigarette should be encouraged to try products such as blu as an alternative to smoking. It is also clear from the data that vapers who continue to smoke, termed dual users, are undergoing a longer-term transition from smoking to non-smoking, moving through different stages of use that are not evident in snapshot surveys," said Dr O'Connell.

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The complete study can be downloaded here: http://www.mdpi.com/1660-4601/15/9/1914

*1. Cheung, Y.T.D., et al., Nicotine replacement therapy to aid gradual cessation in smokers with no intention to quit: Association between reduction quantity and later abstinence. Preventive Medicine Reports, 2015. 2: p. 196-201.

2. Castaldelli-Maia, J.M., PUB077 Cytisine versus Nicotine Replacement Treatment Real-Life Effectiveness for Smoking Cessation. Journal of Thoracic Oncology, 2017. 12(1): p. S1492-S1493.

3. Taylor, G.M.J., et al., The effectiveness of varenicline versus nicotine replacement therapy on long-term smoking cessation in primary care: a prospective cohort study of electronic medical records. International Journal of Epidemiology, 2017. 46(6): p. 1948-1957.

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