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In Mice, Mother's Immunity to Dengue Promotes Microcephaly-Like Syndrome in Fetuses (1 of 2)

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American Association for the Advancement of Science (AAAS)

In Mice, Mother's Immunity to Dengue Promotes Microcephaly-Like Syndrome in Fetuses (1 of 2)

image: A comparison of the size of the heads of fetuses from uninfected mothers, fetuses from Zika virus infected mothers, and fetuses from Zika virus infected mothers that are immune to dengue. A mild microcephaly phenotype is observed with Zika infection, but severe microcephaly is observed with Zika infection when maternal antibodies to dengue are present. This material relates to a paper that appeared in the Feb. 27th, 2019, issue of Science Advances, published by AAAS. The paper, by A.P.S. Rathore at Duke-National University of Singapore in Singapore, and colleagues was titled, "Maternal immunity and antibodies to dengue virus promote infection and Zika virus-induced microcephaly in fetuses." view more 

Credit: [Credit: Rathore & Saron et al. Science Advances 2019]


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