image: Cells in prophase (left) and anaphase (right) are showing histones and 3-D tracks of growing microtubule ends, color coded by velocity. Color coding of each track by height or growth phase lifetime is also possible. Each image in A represents a distillation of a few time points from a 4-D, two-color data set typically covering hundreds of time points per cell. Graph shows the distribution of growth rates at different stages of mitosis, averaged across nine to twelve cells. This material relates to a paper that appeared in the 24 Oct. 2014 issue of Science, published by AAAS. The paper, by B.-C. Chen at Howard Hughes Medical Institute in Ashburn, VA, and colleagues was titled, "Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution." view more
Credit: [Credit: Betzig Lab, HHMI]