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Wiggling Worms Offer Clues to Reperfusion Injury (1 of 2)

Reports and Proceedings

American Association for the Advancement of Science (AAAS)

Wiggling Worms Offer Clues to Reperfusion Injury (1 of 2)

image: The nematode C. elegans responds to reoxygenation by increasing its speed (the O2-ON response). Shown are the worm tracks from 9 periods of a movie recording the C. elegans response to oxygen restoration, tiled in a 3 by 3 grid, meant to be read from left to right, top to bottom. The first frame shows the tracks made during a 1-minute interval in the presence of normal levels of oxygen (20%). The next 5 frames show 1-minute intervals with no oxygen. The final 3 frames show the worm tracks when 20% oxygen is restored. A palette of 16 colors is used to distinguish worm tracks, and the same color can be reused for different worms in the same image. Furthermore, the color of a worm's track in one image does not map to the same color in the next image. Finally, if worms collide and separate again, new colors are assigned to the worms' tracks. This image relates to a paper that appeared in the June 27, 2013, issue of Science Express, published by AAAS. The paper, by Dengke K. Ma at Howard Hughes Medical Institute in Cambridge, MA, and colleagues was titled, "Cytochrome P450 Drives a HIF-Regulated Behavioral Response to Reoxygenation by C. elegans." view more 

Credit: [Image courtesy of Nikhil Bhatla and Dengke Ma]


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