News Release

冠状病毒的跨物种传播能力

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

科研人员报告说,猪德尔塔冠状病毒(PDCoV)的S蛋白与氨肽酶N(APN)这种蛋白质的一个域结合,后者在宿主细胞表面表达,并且在各动物物种中高度保守;猪、人类、鸡和猫的氨肽酶N(APN)的表达促进了猪德尔塔冠状病毒(PDCoV)感染培养的细胞,这提示了猪德尔塔冠状病毒(PDCoV)从猪传给其他物种的一个可能的机制。

论文 #18-02879: "Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility," 作者 Wentao Li 等人

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媒体联系人:Linda J. Saif,美国俄亥俄农业研究发展中心,俄亥俄州立大学
Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH;
电话: 330-263-3744, 419-846-3011;
电子邮件:<saif.2@osu.edu>;

媒体联系人:Berend-Jan Bosch,荷兰乌得勒支大学
Utrecht University, NETHERLANDS;
电话: 31-30-2534195;
电子邮件:b.j.bosch@uu.nl


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