image: Scans of two mice treated with ISRIB after 1 and 6 weeks. The mouse with mutations in PTEN and MYC (bottom row) showed tumor regression (red line) 6 weeks after treatment with no signs of toxicity. This material relates to a paper that appeared in the 2 May, issue of Science Translational Medicine, published by AAAS. The paper, by H.G. Nguyen at Helen Diller Family Comprehensive Cancer Center in San Francisco, CA; and colleagues was titled, "Development of a stress response therapy targeting aggressive prostate cancer." view more
Credit: H.G. Nguyen <i>et al., Science Translational Medicine <i/>(2018)