News Release 9-Mar-2020

脑细胞的免疫受体与抑郁症

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

Neuron-Glia Coculture Stained for Neuronal Map2 and Pre- and Postsynaptic Proteins vGlut1 and Homer — **image: Neuron-glia coculture stained for neuronal Map2 (blue) and pre- and postsynaptic proteins vGlut1 (green) and Homer (red) respectively.** view more

Credit: Image courtesy of Daniela Alí-Ruiz

1100人参与的一项研究发现，影响大脑小胶质细胞的CD300f免疫受体的一个多态，与保护女性免于罹患重症抑郁有关联，而敲除雌性小鼠的这种免疫受体导致了与重症抑郁相符的行为；这组作者说，这些结果提示了小胶质细胞及其免疫受体在神经精神疾病中的一个作用。

###

Journal

Proceedings of the National Academy of Sciences

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.