image: Located inside the treatment room, a steel gantry can rotate around a patient to aim the proton beam at the correct angle to deliver treatment. Powerful magnets located outside the room guide the high-speed, high-energy protons into a beamline, an airless tube about as long as a football field. From the beamline, protons are channeled into the gantry. view more
Credit: The Children's Hospital of Philadelphia
The Children's Hospital of Philadelphia announces the availability of proton therapy, a precise form of cancer radiation that offers potentially life-changing benefits to children with brain tumors and other solid tumors. The Hospital's Cancer Center has recently begun using proton treatment at the new Roberts Proton Therapy Center, a cutting-edge radiation oncology facility located across the street from Children's Hospital in Penn Medicine's Perelman Center for Advanced Medicine.
With a child diagnosed with a brain tumor, parents often face a cruel dilemma. Conventional radiation treatment that offers survival often risks severe side effects, including damage to surrounding healthy tissue, as well as impairments to hearing, vision, growth and cognition. The after-effects may impede a child's daily life and may carry the prospect of lifelong disability and dependence. In fact, the side effects are potentially devastating enough that conventional radiation therapy is not given to children under age two.
The Roberts Proton Therapy Center is the only proton therapy facility in the country conceived with pediatric patients in mind from the earliest planning stages. Children who receive proton therapy in this $140 million state-of-the-art facility benefit from a long-standing collaboration between Children's Hospital and radiation oncologists at Penn Medicine. Young patients experience family-focused pediatric care from a medical team who understands the unique needs of children with cancer, while providing emotional support for the entire family. Every detail has been considered-- from scheduling morning treatments for children who cannot eat prior to anesthesia, to offering a dedicated child-oriented waiting room and a dedicated pediatric anesthesia room.
"When the Roberts Proton Therapy Center's pediatric program is fully operational, the Cancer Center at Children's Hospital will be able to treat more children with proton therapy than all other American proton centers combined, thereby reducing the negative impact of cancer therapy for children from the Philadelphia region and around the country" said John M. Maris, M.D., chief of Oncology and director of the Cancer Center at The Children's Hospital of Philadelphia.
With its extensive program of comprehensive services, the Cancer Center is one of the largest pediatric cancer programs in the United States. All cancer care is available at one location, including doctor's visits, lab work and a full range of therapies. In its most recent listings, U.S. News & World Report ranked Children's Hospital first in cancer care among America's children's hospitals.
In addition to its application for brain tumors, proton therapy may also be appropriate for cancers of the head and neck, and tumors located near the spinal cord, heart and lungs—sites perilously close to vital organs.
The advent of proton therapy provides a dramatic reduction in side effects when compared to conventional radiation. Because protons can be more precisely aimed and concentrated on a tumor, much less energy impacts normal tissue in front of and behind the cancerous mass. At the same time, doctors may increase the radiation dose focused on the tumor for optimum benefits.
Protons are positively charged particles, found in the nucleus of every atom, but made available in this therapy by stripping away electrons from hydrogen atoms. Although commonly manipulated by physicists in high-energy particle accelerators in research settings since the mid-20th century, protons are only gradually becoming part of medical practice. There are currently only seven proton therapy centers in the United States.
Note to reporters: For further information, including interviews with Children's Hospital caregivers and with families of children receiving proton therapy, contact Rachel Salis-Silverman at 267-426-6063; Salis@email.chop.edu
About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking second in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 460-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the University of Pennsylvania School of Medicine (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $3.6 billion enterprise.
Penn's School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools, and is consistently among the nation's top recipients of funding from the National Institutes of Health, with $367.2 million awarded in the 2008 fiscal year.