image: Mice treated with idazoxan, which blocks a receptor for norepinephrine, behaved similarly to control animals despite still having amyloid-beta plaques in the brain. This material relates to a paper that appeared in the Jan. 15, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by F. Zhang at University of Alabama at Birmingham in Birmingham, AL; and colleagues was titled, "Amyloid β redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade." view more
Credit: F. Zhang <i>et al., Science Translational Medicine</i> (2019)