image: This image shows the external face of the flavivirus NS1 protein (sugars in grey balls) is exposed on infected cell surfaces where it can interact with the immune system. This face is also exposed in secreted NS1 particles present in patient sera. The background image shows artificial membranes coated with the NS1 protein. This image relates to a paper that appeared in the Feb. 6, 2014, issue of Science Express, published by AAAS. The paper, by David L. Akey at the University of Zurich in Zurich, Switzerland, and colleagues was titled, "Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation." view more
Credit: Image courtesy of David Akey, Somnath Dutta