About The Study: This cohort study found no significant association between the preoperative use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and short-term postoperative aspiration pneumonia despite growing concerns about the adverse effects of these medications after surgery. This finding suggests that it may be beneficial to reassess the preoperative withholding guidelines for GLP-1 RAs.
Corresponding author: To contact the corresponding author, Eric L. Smith, M.D., email esmith@nebh.org.
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(doi: 10.1001/jamanetworkopen.2025.0081)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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