New computational method reveals congestive heart failure

A team of physicists at Tampere University has developed a groundbreaking method for detecting congestive heart failure with greater ease and precision than previously thought possible. This multidisciplinary study, involving both cardiologists and computational physicists, builds on the team’s earlier breakthroughs, for example, in predicting the risk of sudden cardiac death.

Researchers at Tampere University have achieved a major milestone in diagnosing heart diseases. According to their new study, congestive heart failure can be reliably detected by analysing the intervals between successive heartbeats – inter-beat or RR intervals – which can be measured not only with professional equipment but also with smartwatches and heart rate monitors.

The new method is based on advanced time-series analysis developed by the Quantum Control and Dynamics research group led by Professor Esa Räsänen. This analysis allows the investigation of dependencies between inter-beat intervals at different time scales, along with other complex characteristics typical of various heart diseases.

The researchers analysed multiple international databases containing long-term electrocardiographic (ECG) recordings from healthy control subjects and patients suffering from heart disease. The study particularly focused on distinguishing patients with congestive heart failure from healthy control subjects and patients with atrial fibrillation. The new method was capable of detecting congestive heart failure with an accuracy of 90%, demonstrating its effectiveness and reliability as a diagnostic tool.

More affordable and accessible cardiac monitoring

Currently, diagnosing congestive heart failure often requires costly and time-consuming imaging techniques, such as echocardiography, also known as cardiac ultrasound. Detecting congestive heart failure from inter-beat intervals alone has previously been extremely difficult or virtually impossible in patients with a regular sinus rhythm. In contrast, atrial fibrillation is much easier to detect and can already be identified using many of the consumer devices available on the market.

The new method provides a much easier and more cost-effective means for screening congestive heart failure, for example, with consumer-grade heart rate devices and smartwatches. This could lead to the earlier detection of cardiac diseases, thereby improving patients’ treatment and prognosis.

“The new method opens up new opportunities for digital healthcare and patient self-monitoring,” says the lead author of the study, Doctoral Researcher Teemu Pukkila.

“Our findings pave the way for the early detection of congestive heart failure using readily available equipment, eliminating the need for complex diagnostic procedures,” says Professor of Cardiology Jussi Hernesniemi, who participated in the study and also works as a cardiologist at Tays Heart Hospital.

The methods developed by the Quantum Control and Dynamics group have previously been used, among other things, to detect sudden cardiac death and assess physiological thresholds in endurance sports. The next step for the researchers is to verify the results with more extensive data and examine how similar methods could more accurately detect other heart diseases. The results are a promising indication that advanced algorithms can revolutionise the diagnostics and treatment of cardiovascular diseases.

The research paper was published in Heart Rhythm O2 on 31 January 2025.