News Release

New research promises an unprecedented look at how psychosocial stress affects military service members’ heart health

UMass Amherst researcher awarded $1 million grant from Defense Department to analyze data from the Millenium Cohort Study

Grant and Award Announcement

University of Massachusetts Amherst

A University of Massachusetts Amherst researcher will examine the role of cumulative psychosocial stress – as well as race, ethnicity and gender – among U.S. military personnel to gauge their impact on cardiovascular health and healthcare utilization.

The study is funded with a $1 million grant from the Defense Health Agency, part of the Department of Defense (DoD). The findings will help the military develop programs for health promotion and health readiness for active duty and Reserve/National Guard personnel. 

“One of the priorities of the Defense Health Agency is informing health promotion efforts for service members’ readiness and well-being,” says lead investigator Daniel López-Cevallos, associate professor of community health education in the School of Public Health and Health Sciences. “The strength of our study is that we are able to look at child abuse and neglect, bias and discrimination, and military stressors associated with health outcomes. We will be able to assess both the overall stress burden, as well as identify specific stressors that can affect heart health of U.S. service members.”

López-Cevallos is collaborating with Sheila Castañeda, a research epidemiologist in the Deployment Health Department at the Naval Health Research Center and deputy principal investigator of the Millenium Cohort Study. This cohort is the largest and longest-running prospective health study in U.S. military history, with more than 260,000 service members enrolled since 2001. The study is designed to examine the effects of military service on long-term health outcomes of service members and veterans.

The researchers will analyze survey data and DoD administrative and healthcare records from more than 58,000 military personnel who enrolled in the study in 2020-2021. Those participants were surveyed about adverse childhood experiences, experiences of hazing, bullying and discrimination, combat experiences, health diagnoses and other stressful life events.

“Previous epidemiological research indicates social determinants of health, such as increased exposure to stress, may contribute to cardiovascular disease disparities among certain racial and ethnic civilian groups,” Castañeda says. “Our study will determine the role of cumulative stress on heart health among service members in hopes of determining targets for integrated prevention efforts.” 

In addition to measuring the associations between various stressors and cardiovascular health, López-Cevallos and Castañeda will look at the moderating effects of protective factors – such as post-traumatic growth, social support, unit cohesion and military satisfaction – on the relationship between cumulative psychosocial stress and health outcomes. 

“One of the things we’re able to do in this study is to look at the cumulative or synergistic effects of experiencing multiple, both acute and chronic, stressors,” López-Cevallos says. “There is little research that has looked at disparities by gender and among racial and ethnic groups within the military.”

The researchers will use the American Heart Association’s Life’s Essential 8, which are key measures of cardiovascular health, in their analysis. They include health behaviors, such as eating and sleeping well and not using tobacco, and health factors, such as blood pressure, cholesterol, diabetes and body mass index. 

“We will look at the aggregate levels of stress of these service members and then also get more specific to tease out individual stressors, such as adverse childhood experiences or experiences with harassment and discrimination. Then we can recommend areas of focus within the military to inform programmatic and policy priorities,” López-Cevallos says.

Another goal is to effect better cardiovascular outcomes and reduce healthcare system burdens by addressing the psychosocial stressors. “The theory here is to tackle those upstream factors that would otherwise erode health outcomes and also increase utilization of more complex health services,” he adds.


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