News Release

Breast cancer in users of levonorgestrel-releasing intrauterine systems

JAMA

Peer-Reviewed Publication

JAMA Network

About The Study: This Danish nationwide study found an association between levonorgestrel-releasing intrauterine system (LNG-IUS) use and increased breast cancer risk in females ages 15 to 49, compared with nonuse. LNG-IUS use constitutes the preferred hormonal contraception among Danish premenopausal women older than 30 years. Although the absolute breast cancer risk is low in young women, this study found an excess risk of 14 per 10,000 females. The risk did not increase with duration of use.

Corresponding Author: To contact the corresponding author, Lina Steinrud Mørch, MSc, PhD, email morch@cancer.dk.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.18575)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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