About The Study: In this study, a higher burden of comorbidity was associated with worse clinical outcomes in people with multiple sclerosis (MS), although comorbidity could potentially be a partial mediator of other negative prognostic factors. The findings suggest a substantial adverse association of the comorbidities investigated with MS disease activity and that prevention and management of comorbidities should be a pressing concern in clinical practice.
Corresponding Author: To contact the corresponding author, Amber Salter, PhD, email amber.salter@utsouthwestern.edu.
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(doi:10.1001/jamaneurol.2024.2920)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the European Committee for Treatment and Research in Multiple Sclerosis 2024 Annual Congress.
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Journal
JAMA Neurology