Designing a normative neuroimaging library to support diagnosis of traumatic brain injury

With recent advances in neuroimaging, moving from qualitative to quantitative outputs, an understanding is needed of what normal data look like to be able to apply these advances to diagnosis and outcomes prediction in traumatic brain injury (TBI). A new article in the peer-reviewed Journal of Neurotrauma introduces the large Normative Neuroimaging Library (NLL) to the research community. Click here to read the article now.

The American College of Radiology and Cohen Veterans Bioscience created a reference database of healthy individuals with neuroimaging, demographic data, and characterization of psychologic functioning and neurocognitive data. NNL consists of data collected from about 1900 healthy participants across a diverse population.

“On its release, NNL is poised to support the use of advanced imaging in clinician decision support tools, the validation of imaging biomarkers, and the investigation of brain-behavior anomalies, moving the field toward precision medicine,” stated Allyson Gage, Chief Medical Officer at Cohen Veterans Bioscience, and coauthors.

“My congratulations to Dr. Gage and colleagues for this important effort. I predict that this normative neuroimaging library will serve as a cornerstone for many important future investigations in TBI as well as a wide variety of other conditions. Visionary forward-looking work,” says David L. Brody, MD, PhD, Editor-in-Chief of Journal of Neurotrauma.

About the Journal
Journal of Neurotrauma is an authoritative peer-reviewed journal published 24 times per year in print and online that focuses on the latest advances in the clinical and laboratory investigation of traumatic brain and spinal cord injury. Papers and reviews focus on clinical trials, fluid biomarkers, imaging, clinical studies, pathophysiological mechanisms, translational therapeutics, and biomechanics. Journal of Neurotrauma is the official journal of the National Neurotrauma Society and the International Neurotrauma Society. Complete tables of content and a sample issue may be viewed on the Journal of Neurotrauma website.

About the Publisher
Mary Ann Liebert, Inc. is a global media company dedicated to creating, curating, and delivering impactful peer-reviewed research and authoritative content services to advance the fields of biotechnology and the life sciences, specialized clinical medicine, and public health and policy. For complete information, please visit the Mary Ann Liebert, Inc. website.