About The Study: Prescriptions for first-generation antihistamines were associated with a 22.0% higher seizure risk in children, especially in those ages 6 to 24 months in this cohort study. These findings emphasize the need for careful and judicious prescription of first-generation antihistamines in young children and underline the need for further research to elucidate associations between antihistamine prescriptions and seizure risk.
Corresponding Authors: To contact the corresponding authors, email Seonkyeong Rhie, MD, (starclusters@gmail.com) and Man Yong Han, MD, (drmesh@gmail.com).
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(doi:10.1001/jamanetworkopen.2024.29654)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Journal
JAMA Network Open