image: Immunofluorescence staining of human primary gastric cells grown in a microplate and infected with Chlamydia trachomatis (blue: cell nuclei, green: C. trachomatis, grey: actin).
Credit: Pargev Hovhannisyan, University of Würzburg, CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)
Chlamydia can infect gastrointestinal epithelial cells in the lab, supporting the theory that the bacterium can form a reservoir in the human gut.
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Article URL: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012144
Article Title: Infection of human organoids supports an intestinal niche for Chlamydia trachomatis
Author Countries: Germany, India
Funding: This work was funded by the Deutsche Forschungsgemeinschaft (DFG) in the RTG 2157/2 3D Infect and the SFB 1583 DECIDE to S.B., T.R. and the European Research Council (grant no. ERC-2018-ADG/NCI-CAD) to T.R. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Journal
PLOS Pathogens
Article Title
Infection of human organoids supports an intestinal niche for Chlamydia trachomatis
Article Publication Date
22-Aug-2024
COI Statement
Competing Interests: The authors have declared that no competing interests exist.