Bridging research, perspectives, and clinical excellence in skin aging at the 15th International Conference on Skin Challenges 2024

The 15th International Conference on Skin Ageing & Challenges will be organized on November 5-6, 2024, at the Corinthia Palace in Malta, in collaboration with the International Society of Microbiota (ISM). The conference will explore innovative strategies to understand and combat skin aging. Topics will include targeting senescent cells with senolytics, utilizing extracellular vesicles for rejuvenation, and exploring the benefits of microbiota and mitochondrial transplantation. International speakers will also delve into the symbiotic relationship between the microbiome and skin health, as well as cutting-edge therapies in phage therapy and iron metabolism.

 

Skin Challenges 2024 Trends

1. Senolytics: Targeting Senescent Cells

• Mechanisms by which senolytics target and eliminate senescent cells.
• Recent advances in senolytic drugs and their application in skin aging.
• Clinical trial results and potential side effects of senolytic therapies.

Speakers include:

Karin Scharffetter-Kochanek, Universitätsklinikum Ulm, Germany – Reversing Skin Aging: The Power of Senomorphics and Senolytics

Markus Schosserer, Medical University of Vienna, Austria – The Epitranscriptome and snoRNAs in Cellular Senescence and Skin Aging –

 

 2. Extracellular Vesicles: Messengers for Skin Rejuvenation

• The role of extracellular vesicles (EVs) in skin health and regeneration.
• Methods for isolating and utilizing exosomes in anti-aging treatments.
• Clinical and preclinical studies demonstrating the efficacy of exosome-based therapies.

 

3. Skin Microbiota / Mitochondria Transplantation: A Novel Approach

• Techniques and benefits of skin microbiota transplantation.
• Advances in mitochondrial transplantation and its impact on skin aging.
• Combined approaches to restoring skin microbiota and mitochondrial function.

Speakers include:

Andrés Caicedo, Universidad San Francisco de Quito USFQ, Ecuador – Exploring Mitochondrial Dynamics and Transfer: Implications for Skin Aging and Novel Therapeutic Approaches

 

4. Microbiome & Skin: The Symbiotic Relationship

• The interaction between the skin microbiome and skin health.
• Factors influencing the skin microbiome and strategies to maintain its balance.
• Innovations in microbiome-based skincare products and treatments.

Speakers include:

Julia Oh, The Jackson Laboratory, USA – Age, Frailty and Infection Risk Reservoirs: The Skin Microbiome of Older Adults

 

 5. Mitochondrial Function: Powerhouses of the Skin Cells

• The importance of mitochondrial function in skin cells and its decline with age.
• Nutritional and lifestyle interventions to enhance mitochondrial function.
• Emerging therapies aimed at boosting mitochondrial health to combat skin aging.

 

6. Olfactory Receptors & Skin: Sensing & Signaling

• The role of olfactory receptors in skin physiology and aging.
• Mechanisms by which olfactory receptors influence skin cell behavior.
• Potential therapeutic applications of targeting olfactory receptors for skin health.

Speakers include:

Marvin Edeas, Institut Cochin, INSERM U1016, Université de Paris, France – Olfactory Receptors: Outsider or Misunderstood Key Strategic Player?

Shinobu Nakanishi, Shiseido Co., Japan – Olfactory Receptors, Skin and Keratinization: What do we Know?

 

7. Phage Therapy: Targeting Pathogenic Bacteria

• The role of phage therapy in dermatology, particularly in treating skin infections.
• Comparative studies of phage therapy versus traditional antibiotic treatments.
• Clinical applications and case studies of phage therapy in maintaining skin health.

 

8. Iron Metabolism: Balancing Skin Health

• The impact of iron metabolism on skin health and aging.
• Strategies to manage iron levels for optimal skin function.
• Research on iron-related skin conditions and their treatments.

Speakers include:

Leopold Eckhart, Medical University of Vienna, Austria – Iron Metabolism of the Skin: Recycling versus Release

 

9. Artificial Intelligence, Algorithms and Skin Aging  

• The application of AI and machine learning algorithms in skin aging research.
• AI-driven diagnostics and personalized treatment plans for skin health.
• Innovations in AI technology for predicting and mitigating skin aging processes.

Speakers include:

Jing-Dong J. Han, Peking University, China – Innovative Thermal Imaging Techniques for Detecting Aging Disorders: ThermaFace Method

 

10. Other Innovative Research in Skin Aging

Substances Promising Active Skin Rejuvenation Effectively Support Fast Skin Wound Healing – Andrey Koptyug, Mid Sweden University, Sweden

Biology Underneath the Skin: Employing Nature’s Approach to Skin Rejuvenation – Jill Helms, Stanford University, USA

 

Keynote Speech

Helmut Sies, Heinrich Heine University Düsseldorf, Germany, known for his groundbreaking contributions in oxidative stress research, will deliver the keynote speech. His presentation “Oxidative Stress: Eustress and Distress” will shed light on the intricate balance between beneficial and harmful oxidative stress on skin health.

 

Further information about all Skin Ageing & Challenges conference speakers, topics, abstracts submission, registration and more: www.skin-challenges.com.

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