Multimedia Release

Kotaro Sasaki and his team unveil the genetics of testicular cancer

Researchers develop the first in vitro seminoma model, shedding light on chromosomal anomalies and signaling pathways.

Peer-Reviewed Publication

University of Pennsylvania

Kotaro Sasaki - Main

image: 

The microscopy image shows seminoma tissue in patient’s testis showing large, round cells with clear cytoplasm. The tumor tissue is heavily infiltrated by lymphocytes (small cells with dark/blue nuclei).

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Credit: (Image: Courtesy of Kotaro Sasaki)

Journal

Cell Reports

DOI

10.1016/j.celrep.2024.114323

Method of Research

Experimental study

Subject of Research

Human tissue samples

Article Title

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Article Publication Date

10-Jun-2024

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