image: Age-specific and age-standardized prevalence with 95% confidence intervals (shaded area) of isotretinoin use per 1,000 girls and women aged 13-49 years between 2004 and 2019 in the German Pharmacoepidemiological Research Database (GePaRD).
Credit: Reinold J, et al., 2024, PLOS Medicine, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)
The anti-acne medicine isotretinoin, which can cause defects in a developing fetus, is now used by almost 2 in 1,000 girls and women of childbearing age, according to analysis of German database of 25 million
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In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004339
Article Title: Use of isotretinoin among girls and women of childbearing age and occurrence of isotretinoin-exposed pregnancies in Germany: A population-based study
Author Countries: Germany
Funding: The study was partly funded by the German Federal Institute for Drugs and Medical Devices, Bonn (BfArM, V-18281/ 68605 / 2019-2020) (https://www.bfarm.de). The study proposal was submitted by UH. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Journal
PLOS Medicine
COI Statement
Competing Interests: see manuscript