The schematic diagram (IMAGE)

City University of Hong Kong

The schematic diagram

Caption

The CityU team developed a new class of near-infrared-activated platinum(IV) photo-oxidants that can effectively eliminate cancer cells in an oxygen-independent manner. The photo-oxidants trigger nonclassical necrosis, which can overcome the resistance of cancer cells to conventional photodynamic therapies and chemotherapies, and activate the immune system. The research highlights the importance of the photo-oxidation capability of metal-based anticancer agents and provides a new direction for the development of next-generation anti-cancer drugs.

Credit

Deng, Z. et al., source: https://www.nature.com/articles/s41557-023-01242-w

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