Graphical Abstract Kinase P38 (IMAGE) European Molecular Biology Laboratory Caption Graphical abstract illustrating MAP kinases p38α and MKK interactions and conformation states Credit Credit: Pauline Juyoux/EMBL Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. Adaptations must be shared under the same terms. License CC BY-NC-SA Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.