During failure of core protein quality control in the nematode C. elegans, a specialized anti-aggregation mechanism relying on pathogen response factors and lysosomal mediated degradation is triggered (IMAGE)
Caption
C. elegans head/upper body with aggregates (KIN-19) in the pharynx in control conditions (left) and without aggregates upon proteasome inhibition (right photo).
Credit
Raimund Jung (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)
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CC BY