Controlling cellular stress response with light (IMAGE)
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Integrated Biosciences has genetically modified neuroglioma and osteosarcoma cancer cells so that their integrated stress response (ISR), a key facet of aging, can be activated by light. Through this unique platform, the company has determined that transient stress leads to an adaptive response that protects a cell from damage, whereas prolonged activation of the ISR leads to cell death, shedding light on the processes that determine a cell’s fate decisions with age.
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Integrated Biosciences
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