The capture and release of Mycobacterium tuberculosis bacterial particles by the CAPTURE-XT® chip (VIDEO)
Caption
Video of the capture and release of Mycobacterium tuberculosis bacterial particles visualised by fluorescence microscopy as white fluorescent spots on the edges of the electrodes by dielectrophoresis using the CAPTURE-XT® chip. Solubilized sputum flows across the chip’s electrodes from right to left and gradually bacterial particles accumulate along the edges of the electrodes. As more sputum passes over the electrodes, more bacteria accumulate filling up the electrodes towards the left of the chip, thus providing a direct visual bacterial count in the sputum sample. On release of the dielectrophoretic current (at 47 seconds), all the bacteria are release in one pulse, thus enriching the outflow and allowing for increased sensitivity of detection by molecular methods.
Credit
Moore et al. The Journal of Molecular Diagnostics
Usage Restrictions
Please include attribution.
License
Original content