Pathways to Precision Psychiatry (IMAGE)
Caption
The image on the left reveals a distribution (yellow) of a gene-quieting molecule in mouse brain cells engineered to have a genetic trait associated with schizophrenia. This manipulation leads to full restoration of a key cognitive deficit in the mice. The image on the right shows an organoid—a three-dimensional cell culture derived from brain cells of people with schizophrenia. These can serve as research models for studying the cellular bases of psychiatric conditions and for screening drug candidates.
Credit
Zuckerman Institute/Gogos lab
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Credit must be given to the creator. Only noncommercial uses of the work are permitted. Adaptations must be shared under the same terms.
License
CC BY-NC-SA