SAR analysis (IMAGE)

City University of Hong Kong

SAR analysis

Caption

SAR analysis of the synthetic compounds. The key factors that contribute to the anticancer activity of this type of compound are indicated. The presence of certain substituents, including halogen and hydroxyl groups, at certain positions in the tetraarylmethane compounds significantly improves cytotoxicity. TMS, trimethylsilyl; Me, methyl.

Credit

© Tan, X. et al. https://www.nature.com/articles/s44160-022-00211-4

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