Conventional methods for amide bond formation of nitrogen heterocyclic compounds (IMAGE)

Tohoku University

Conventional methods for amide bond formation of nitrogen heterocyclic compounds

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Conventional methods for N-acylation of heterocyclic, nitrogen-containing compounds are notoriously inefficient, producing low yields and often involving preactivated reagents, strong metal bases and clean-up steps.

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Atsushi Umehara

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